Innate Immune Responses to Chimpanzee ... | 台北市立動物園資訊網
2020年11月30日—InnateImmuneResponsestoChimpanzeeAdenovirusVector155VaccinationinMiceandMonkeys...Replication-deficientchimpanzee ...
IntroductionReplication-incompetent adenovirus (Ad) vectors, such as those based on the well-studied human Ad serotype 5 (Ad5), are employed as vaccine delivery vehicles due to their high manufacturing efficiency, versatility, and capacity to accommodate large transgenes (1). They also enable efficient transduction of dividing and non-dividing cells without chromosomal integration (2). Owing to their lower seroprevalence and thus decreased vector neutralization in humans as compared to human Ad5, chimpanzee Ad (ChAd) vectors represent an attractive vaccine platform (3–5). ChAd-vectored candidate vaccines against infectious diseases such as malaria, Ebola, and RSV have shown favorable immunogenicity and tolerability in humans (6–11). These vaccines drive robust intracellular antigen expression, thus promoting a CD8+ T-cell-biased response, but were also shown to induce antigen-specific ...
Development of novel vaccine vectors ... | 台北市立動物園資訊網
Chimpanzee adenoviral vectors as vaccines for outbreak ... | 台北市立動物園資訊網
Chimpanzee Adenovirus Antibodies in Humans | 台北市立動物園資訊網
Is it true? Does the OxfordAstraZeneca vaccine contain ... | 台北市立動物園資訊網
A single intranasal dose of chimpanzee adenovirus | 台北市立動物園資訊網
Innate Immune Responses to Chimpanzee ... | 台北市立動物園資訊網
Chimpanzee adenoviral vectors as vaccines | 台北市立動物園資訊網
Replication | 台北市立動物園資訊網
What are Adenovirus | 台北市立動物園資訊網
Development of novel vaccine vectors | 台北市立動物園資訊網
【黑猩猩】:;瀕臨絕種保育類野生動物
臉部為黑色無毛鬚,眉脊隆起;頭部有毛髮,成年後會略禿;小黑猩猩的鼻子、耳朵、手掌及腳掌為肉色,身體部份的膚色則每一隻...
【人猿】:人猿人科;極危 CR
粗糙而稀疏的毛顏色會隨著年齡改變,從幼年鮮明的橘色到成年動物的紅褐色,有些還會轉變成深巧克力色。額頭高,鼻口凸出。手...